Recommended Reading on Atherosclerosis and Vascular Biology

ESC Working Group on Atherosclerosis and Vascular Biology

Date

Title

• Date: 21/04/2025
  Title: Distinct inflammatory pathways shape atherosclerosis in different vascular beds
• Date: 21/04/2025
  Title: Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification
• Date: 21/04/2025
  Title: Targeting the PDK/PDH axis modulates neutrophil and smooth muscle cell pathological responses and prevents abdominal aortic aneurysm formation.
• Date: 01/02/2025
  Title: SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance
• Date: 01/02/2025
  Title: Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis
• Date: 01/02/2025
  Title: Cardioprotection exerted by intravenous statin at index myocardial infarction event attenuates cardiac damage upon recurrent infarction
• Date: 01/12/2024
  Title: Pathogenesis of atherothrombotic events: from lumen to lesion and beyond
• Date: 01/12/2024
  Title: Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node
• Date: 01/12/2024
  Title: Plasma proteome and incident myocardial infarction: sex-specific differences
• Date: 01/10/2024
  Title: Atherosclerotic plaque-specific methylation biomarkers in plasma cell-free DNA of female and male patients with coronary artery disease
• Date: 01/10/2024
  Title: Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming
• Date: 01/10/2024
  Title: Systemic inflammation and health outcomes in patients receiving treatment for atherosclerotic cardiovascular disease
• Date: 01/08/2024
  Title: Myocardial infarction drives trained immunity of monocytes, accelerating atherosclerosis
• Date: 01/08/2024
  Title: Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis
• Date: 01/08/2024
  Title: Atherosclerosis in ancient mummified humans: the global HORUS study
• Date: 01/06/2024
  Title: Single-Cell RNA sequencing reveals an immune landscape of CD4+ T Cells in coronary culprit plaques with acute coronary syndrome in humans—brief report
• Date: 01/06/2024
  Title: Transportation-related carbon footprint of coronary heart disease ambulatory care in the united states
• Date: 01/06/2024
  Title: Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion
• Date: 01/04/2024
  Title: TREM2 protects from atherosclerosis by limiting necrotic core formation
• Date: 01/04/2024
  Title: Understanding and controlling the increasing burden of cardiovascular diseases in Africa
• Date: 01/04/2024
  Title: Rewiring Endothelial Sphingolipid metabolism to favor S1P over ceramide protects from coronary atherosclerosis
• Date: 01/02/2024
  Title: Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin
• Date: 01/02/2024
  Title: Inhibition of a novel Dickkopf-1-LDL receptor–related proteins 5 and 6 axis prevents diabetic cardiomyopathy in mice
• Date: 01/02/2024
  Title: Circulating GDF11 exacerbates myocardial injury in mice and associates with increased infarct size in humans
• Date: 01/02/2024
  Title: Single-cell transcriptomics reveals crucial cell subsets and functional heterogeneity associated with carotid atherosclerosis and cerebrovascular events
• Date: 01/02/2024
  Title: Brain-splenic immune system interactions in hypertension: cellular and molecular mechanisms
• Date: 01/02/2024
  Title: Unraveling the role of sex in endothelial cell dysfunction: evidence from lineage tracing mice and cultured cells
• Date: 01/02/2024
  Title: 4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification
• Date: 01/02/2024
  Title: Sox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness
• Date: 01/02/2024
  Title: Disturbed sleep supports neutrophil activation and promotes atherosclerosis and plaque necrosis
• Date: 01/02/2024
  Title: Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice
• Date: 01/02/2024
  Title: Assessment of subclinical atherosclerosis in asymptomatic people in vivo: measurements suitable for biomarker and mendelian randomization studies
• Date: 01/02/2024
  Title: Single-cell profiling reveals age-associated immunity in atherosclerosis
• Date: 01/02/2024
  Title: Alkaline ceramidase 1–mediated platelet ceramide catabolism mitigates vascular inflammation and abdominal aortic aneurysm formation
• Date: 01/02/2024
  Title: Apoa-i protects pancreatic β-cells from cholesterol-induced mitochondrial damage and restores their ability to secrete insulin
• Date: 01/12/2023
  Title: Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease
• Date: 01/12/2023
  Title: Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
• Date: 01/12/2023
  Title: Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society
• Date: 01/10/2023
  Title: Thrombin-activated interleukin-1α drives atherogenesis, but also promotes vascular smooth muscle cell proliferation and collagen production
• Date: 01/10/2023
  Title: Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.
• Date: 01/10/2023
  Title: Culprit plaque morphology determines inflammatory risk and clinical outcomes in acute coronary syndrome
• Date: 08/08/2023
  Title: Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stres
• Date: 08/08/2023
  Title: Air pollution and plaque healing in acute coronary syndromes
• Date: 08/08/2023
  Title: Protective Effect of Ticagrelor Against Infective Endocarditis Induced by Virulent Staphylococcus aureus in Mice
• Date: 08/08/2023
  Title: JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study
• Date: 08/08/2023
  Title: Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis
• Date: 08/08/2023
  Title: Distinct Roles of DRP1 in Conventional and Alternative Mitophagy in Obesity Cardiomyopathy
• Date: 08/08/2023
  Title: Peripheral ischemia imprints epigenetic changes in hematopoietic stem cells to propagate inflammation and atherosclerosis
• Date: 08/08/2023
  Title: NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis
• Date: 08/08/2023
  Title: Single-cell profiling reveals age-associated immunity in atherosclerosis
• Date: 08/08/2023
  Title: Flow-induced reprogramming of endothelial cells in atherosclerosis
• Date: 13/04/2023
  Title: Immobility-associated thromboprotection is conserved across mammalian species from bear to human.
• Date: 01/04/2023
  Title: Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk
• Date: 01/04/2023
  Title: Single-cell T cell receptor sequencing of paired human atherosclerotic plaques and blood reveals autoimmune-like features of expanded effector T cells
• Date: 01/04/2023
  Title: EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy
• Date: 01/04/2023
  Title: Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
• Date: 27/03/2023
  Title: Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure.
• Date: 06/03/2023
  Title: Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials
• Date: 01/02/2023
  Title: Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells
• Date: 01/02/2023
  Title: Tyrosine-protein kinase yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
• Date: 01/02/2023
  Title: Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation
• Date: 01/04/2022
  Title: Prothymosin alpha: a novel contributor to estradiol receptor alpha-mediated CD8⁺ T-cell pathogenic responses and recognition of type 1 collagen in rheumatic heart valve disease
• Date: 01/04/2022
  Title: Targeting platelet-derived CXCL12 impedes arterial thrombosis
• Date: 01/04/2022
  Title: Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques
• Date: 16/11/2021
  Title: Palmdelphin regulates nuclear resilience to mechanical stress in the endothelium
• Date: 11/10/2021
  Title: H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
• Date: 30/07/2021
  Title: Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span
• Date: 19/07/2021
  Title: Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis
• Date: 09/07/2021
  Title: CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis
• Date: 18/06/2021
  Title: Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
• Date: 24/05/2021
  Title: Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci
• Date: 11/05/2021
  Title: High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
• Date: 17/03/2021
  Title: The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
• Date: 10/03/2021
  Title: Prosaposin mediates inflammation in atherosclerosis
• Date: 16/02/2021
  Title: Sex-Stratified Gene Regulatory Networks Reveal Female Key Driver Genes of Atherosclerosis Involved in Smooth Muscle Cell Phenotype Switching
• Date: 12/01/2021
  Title: RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice
• Date: 02/12/2020
  Title: ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies
• Date: 26/11/2020
  Title: HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry
• Date: 25/11/2020
  Title: Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting
• Date: 02/11/2020
  Title: Neutralization of S100A4 induces stabilization of atherosclerotic plaques: role of smooth muscle cells
• Date: 20/10/2020
  Title: Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs
• Date: 20/09/2020
  Title: Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression
• Date: 15/09/2020
  Title: Sirtuin 5 promotes arterial thrombosis by blunting the fibrinolytic system
• Date: 15/09/2020
  Title: Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression
• Date: 14/08/2020
  Title: Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans
• Date: 17/07/2020
  Title: Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis
• Date: 02/06/2020
  Title: Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization
• Date: 01/06/2020
  Title: High-density Lipoprotein Remodelled in Hypercholesterolaemic Blood Induce Epigenetically Driven Down-Regulation of Endothelial HIF-1α Expression in a Preclinical Animal Model
• Date: 18/05/2020
  Title: Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels
• Date: 02/05/2020
  Title: Endothelial cell infection and endotheliitis in COVID-19
• Date: 01/04/2020
  Title: Sex-specific adipose tissue imprinting of regulatory T cells
• Date: 02/03/2020
  Title: Hematopoietic Cell–Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance
• Date: 01/01/2020
  Title: Long-lasting blood pressure lowering effects of nitrite are NO-independent [...]
• Date: 12/12/2019
  Title: Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis
• Date: 09/12/2019
  Title: Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
• Date: 21/11/2019
  Title: Endothelial GLP-1 (Glucagon-Like Peptide 1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension
• Date: 16/11/2019
  Title: Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction
• Date: 05/11/2019
  Title: Extracellular vesicles in metabolic disease
• Date: 18/09/2019
  Title: Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases
• Date: 03/09/2019
  Title: A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography
• Date: 29/07/2019
  Title: Focus on echovascular imaging assessment of arterial disease: complement to the ESC guidelines (PARTIM 1) in collaboration with the Working Group on Aorta and Peripheral Vascular Diseases
• Date: 01/07/2019
  Title: Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries
• Date: 01/05/2019
  Title: Albuminuria, the HDL (High-Density Lipoprotein) Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus
• Date: 01/05/2019
  Title: MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs
• Date: 12/03/2019
  Title: Relationship of Iron Deposition to Calcium Deposition in Human Aortic Valve Leaflets
• Date: 07/03/2019
  Title: Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities
• Date: 19/02/2019
  Title: Diabetic endothelial colony forming cells have the potential for restoration with glycomimetics
• Date: 01/02/2019
  Title: Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner
• Date: 01/02/2019
  Title: Lysosomal Acid Lipase: From Cellular Lipid Handler to Immunometabolic Target
• Date: 21/01/2019
  Title: Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death
• Date: 27/09/2018
  Title: Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation
• Date: 24/07/2018
  Title: ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages
• Date: 02/07/2018
  Title: PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor