Recommended Reading on Cardiovascular Regenerative and Reparative Medicine

ESC Working Group on Cardiovascular Regenerative and Reparative Medicine

Date

Title

• Date: 21/04/2025
  Title: Foxk1 and Foxk2 promote cardiomyocyte proliferation and heart regeneration
• Date: 21/04/2025
  Title: Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition
• Date: 21/04/2025
  Title: SCN10A-short gene therapy to restore conduction and protect against malignant cardiac arrhythmias
• Date: 01/02/2025
  Title: Identification and regulation of a novel leptin receptor-linked enhancer during zebrafish ventricle regeneration.
• Date: 01/02/2025
  Title: SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance
• Date: 01/02/2025
  Title: Extracellular vesicle-mediated VEGF-A mRNA delivery rescues ischaemic injury with low immunogenicity
• Date: 01/12/2024
  Title: Clinical trials in-a-dish for cardiovascular medicine.
• Date: 01/12/2024
  Title: Noncontractile stem cell-cardiomyocytes preserve post-infarction heart function.
• Date: 01/12/2024
  Title: Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart.
• Date: 01/10/2024
  Title: Efficacy and safety of CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: Rationale and design of the HF-REVERT trial
• Date: 01/10/2024
  Title: Adult cardiomyocytes-derived EVs for the treatment of cardiac fibrosis
• Date: 01/10/2024
  Title: RNA and the emerging potential of bio-inspired molecules in cardiovascular disease therapies
• Date: 01/08/2024
  Title: Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms
• Date: 01/08/2024
  Title: Injury minimization after myocardial infarction: focus on extracellular vesicles
• Date: 01/08/2024
  Title: Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism
• Date: 01/06/2024
  Title: First-in-man use of a cardiovascular cell-derived secretome in heart failure. Case report
• Date: 01/06/2024
  Title: Challenges and perspectives of heart repair with pluripotent stem cell-derived cardiomyocytes
• Date: 01/06/2024
  Title: Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis
• Date: 01/04/2024
  Title: Versatile human cardiac tissues engineered with perfusable heart extracellular microenvironment for biomedical applications
• Date: 01/04/2024
  Title: Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
• Date: 01/04/2024
  Title: Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure
• Date: 01/02/2024
  Title: Gene therapy encoding cell cycle factors to treat chronic ischemic heart failure in rats
• Date: 01/02/2024
  Title: Animal models to study cardiac regeneration
• Date: 01/02/2024
  Title: Aging impairs the neurovascular interface in the heart
• Date: 01/12/2023
  Title: Sfrp1 as a pivotal paracrine factor in the trained pericardial stem cells that foster reparative activity
• Date: 01/12/2023
  Title: Human PSC-derived cardiac cells and their products: therapies for cardiac repair
• Date: 01/12/2023
  Title: Development of a potency assay for CD34+ cell‑based therapy
• Date: 01/10/2023
  Title: Therapeutic silencing of lncRNA RMST alleviates cardiac fibrosis and improves heart function after myocardial infarction in mice and swine
• Date: 01/10/2023
  Title: Am80, a retinoic acid receptor agonist, activates the cardiomyocyte cell cycle and enhances engraftment in the heart
• Date: 01/10/2023
  Title: CCND2 Modified mRNA Activates Cell Cycle of Cardiomyocytes in Hearts With Myocardial Infarction in Mice and Pigs
• Date: 01/04/2023
  Title: TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocyte homeostasis
• Date: 01/04/2023
  Title: Randomized Trial of Targeted Transendocardial Mesenchymal Precursor Cell Therapy in Patients With Heart Failure
• Date: 18/03/2023
  Title: CRISPR-Cas9 editing of TLR4 to improve the outcome of cardiac cell therapy
• Date: 01/02/2023
  Title: Cardiovascular 3D bioprinting: A review on cardiac tissue development
• Date: 01/02/2023
  Title: Toward hierarchical assembly of aligned cell sheets into a conical cardiac ventricle using microfabricated elastomers
• Date: 01/02/2023
  Title: Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components
• Date: 13/01/2023
  Title: Danish phase II trial using adipose tissue derived mesenchymal stromal cells for patients with ischaemic heart failure
• Date: 13/01/2023
  Title: Ablation of CaMKIId oxidation by CRISPR-Cas9 base editing as a therapy for cardiac disease
• Date: 01/04/2022
  Title: The sad plight of cell therapy for heart failure: causes and consequences
• Date: 01/04/2022
  Title: Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles
• Date: 01/04/2022
  Title: Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored
• Date: 23/11/2021
  Title: Basic and Translational Research in Cardiac Repair and Regeneration
• Date: 05/11/2021
  Title: Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study
• Date: 05/11/2021
  Title: FGF10 promotes cardiac repair through a dual cellular mechanism increasing cardiomyocyte renewal and inhibiting fibrosis
• Date: 01/09/2021
  Title: Targeting the Hippo pathway in heart repair
• Date: 01/09/2021
  Title: Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy
• Date: 02/08/2021
  Title: Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy
• Date: 02/08/2021
  Title: Mechanistic and therapeutic distinctions between cardiosphere-derived cell and mesenchymal stem cell extracellular vesicle non-coding RNA
• Date: 02/08/2021
  Title: A perfusable, multifunctional epicardial device improves cardiac function and tissue repair
• Date: 02/08/2021
  Title: Reparative cell therapy for the heart: critical internal appraisal of the field in response to recent controversies
• Date: 01/08/2021
  Title: Cardiomyocyte heterogeneity during zebrafish development and regeneration
• Date: 18/05/2021
  Title: Human engineered heart muscle tissue patches remuscularize the injured heart in a dose-dependent manner
• Date: 21/04/2021
  Title: Mechanistic and therapeutic distinctions between cardiosphere-derived cell and mesenchymal stem cell extracellular vesicle non-coding RNA
• Date: 02/03/2021
  Title: Reparative cell therapy for the heart: critical internal appraisal of the field in response to recent controversies
• Date: 07/01/2021
  Title: Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study
• Date: 01/01/2021
  Title: Immunomodulation by systemic administration of human induced pluripotent stem cell-derived mesenchymal stromal cells to enhance the therapeutic efficacy of cell-based therapy for treatment of myocardial infarction
• Date: 07/10/2020
  Title: Quantitative Hybrid Cardiac (18F)FDG-PET-MRI Images for Assessment of Cardiac Repair by Preconditioned Cardiosphere-Derived Cells.
• Date: 07/10/2020
  Title: Enhancing myocardial repair with CardioClusters.
• Date: 06/08/2020
  Title: Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.
• Date: 01/05/2020
  Title: S100A9 Links Inflammation and Repair in Myocardial Infarction
• Date: 01/05/2020
  Title: Unravelling the Biology of Adult Cardiac Stem Cell-Derived Exosomes to Foster Endogenous Cardiac Regeneration and Repair
• Date: 01/04/2020
  Title: Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes
• Date: 01/01/2020
  Title: Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy
• Date: 01/01/2020
  Title: Tailorable Hydrogel Improves Retention and Cardioprotection of Intramyocardial Transplanted Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice
• Date: 27/11/2019
  Title: Inflammatory Microenvironment of Acute Myocardial Infarction Prevents Regeneration of Heart with Stem Cells Therapy
• Date: 27/11/2019
  Title: Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart
• Date: 30/10/2019
  Title: "Human heart-in-a-Jar": An electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells
• Date: 15/10/2019
  Title: Isolation of Cardiomyocytes Undergoing Mitosis with Complete Cytokinesis
• Date: 05/08/2019
  Title: Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenation
• Date: 02/08/2019
  Title: Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration
• Date: 01/08/2019
  Title: Heterogeneity of Adult Cardiac Stem Cells
• Date: 15/03/2019
  Title: Perspectives on Directions and Priorities for Future Preclinical Studies in Regenerative Medicine.
• Date: 18/02/2019
  Title: Regenerating the field of cardiovascular cell therapy
• Date: 04/02/2019
  Title: Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts
• Date: 22/01/2019
  Title: C-Kit Cells Do Not Significantly Contribute to Cardiomyogenesis During Neonatal Heart Regeneration
• Date: 17/01/2019
  Title: Tissue Engineering and Cell-Based Therapies for Cardiac Repair in Ischemic Heart Disease and Heart Failure
• Date: 28/11/2018
  Title: Regeneration-associated cells
• Date: 06/09/2018
  Title: Hallmarks of cardiac regeneration
• Date: 09/08/2018
  Title: Cardiomyocytes From Vascular Adventitia-Resident Stem Cells
• Date: 06/08/2018
  Title: Mechanisms of Cardiac Repair and Regeneration
• Date: 02/08/2018
  Title: Path Forward for Regenerative Medicine
• Date: 30/03/2018
  Title: Preclinical Studies of Stem Cell Therapy for Heart Disease
• Date: 19/01/2018
  Title: Translational Research in Cardiovascular Repair: A Call for a Paradigm Shift
• Date: 16/01/2018
  Title: Life of Exosomes