Table of Contents
1. Introduction
2. Methods
3. Definitions and classifications
3.1. Definitions
3.2. Classifications
4. Epidemiology and risk factors
5. Pulmonary hypertension diagnosis
5.1. Diagnosis
5.2. Diagnostic algorithm
5.3. Screening and early detection
6. Pulmonary arterial hypertension (group
6.1. Clinical characteristics
6.2. Severity and risk assessment
6.3. Therapy
7. Specific pulmonary arterial hypertension subsets
7.1. Pulmonary arterial hypertension associated with drugs and toxins
7.2. Pulmonary arterial hypertension associated with connective tissue disease
7.3. Pulmonary arterial hypertension associated with human
immunodeficiency virus infection
7.4. Pulmonary arterial hypertension associated with portal hypertension
7.5. Pulmonary arterial hypertension associated with adult congenital
heart disease
7.6. Pulmonary arterial hypertension with signs of venous/capillaries
involvement
7.7. Paediatric pulmonary hypertension
8. Pulmonary hypertension associated with left heart disease (group 2)
8.1. Definition, prognosis, and pathophysiology
8.2. Diagnosis
8.3. Therapy
9. Pulmonary hypertension associated with lung diseases and/or hypoxia (group 3)
9.1. Diagnosis
9.2. Therapy
10. Chronic thrombo-embolic pulmonary hypertension (group 4)
10.1. Diagnosis
10.2. Therapy.
11. Pulmonary hypertension with unclear and/or multi-factorial mechanisms
(group 5)
12. Definition of a pulmonary hypertension centre
12.1. Facilities and skills required for a pulmonary hypertension centre
12.2. Patient associations and patient empowerment