- Biomarkers – Focusing on the proper clinical application of cardiac biomarkers. This group was established by Kristian Thygesen (DK) in 2005 within the former Working Group on Acute Cardiac Care and is now chaired by Nicolas Mills (UK).
- Acute Heart Failure - Highlighting unmet needs and areas of uncertainty in the care of acute heart failure patients. Created in May 2013, this group is under the leadership of Mattia Arrigo (SW).
- Quality Of Care (QoC) - Comprising experts focusing on QoC within acute cardiac care situations, this study group is interdisciplinary and international, under the leadership of Prof. François Schiele (FR) and now chaired by Dr. Sergio Leonardi (IT).
- Spontaneous Coronary Artery Dissection (SCAD) - Working to improve awareness and understanding of this rare coronary artery disease, this group was created in January 2016 under the leadership Prof. Dave Adlam (UK) and now chaired by Dr. Fernando Alfonso (ES).
- EXPERT-PE on Acute Pulmonary Embolism (Acute PE) - An ACVC study group created in 2023, chaired by Prof. Erik Klok (NL).
- Cardiogenic Shock & Cardiac Arrest CSCA - An ACVC Study group created in 2023, chaired by Prof Guido Tavazzi (IT).